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Index > Protein center > Akr1c6(Gene name) > Mouse
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  • Akr1c6 (Gene name),
  • Estradiol 17 beta-dehydrogenase 5 (Protein name ),  DHB5_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Akr1c6(Hsd17b5);
    Protein name:
    Estradiol 17 beta-dehydrogenase 5;
    Alternative:
    17-beta-HSD 5;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Monomer.
    Function:
    Active toward androgens, estrogens, and xenobiotic substrates. Also exhibits low 20 alpha-HSD activity. Shows a-stereospecificity in hydrogen transfer between cofactors and substrates (A-specific). Preferentially catalyzes the reduction of 4-androstenedione, 5-alpha-androstane-3,17-dione, androsterone and dehydroepiandrosterone to testosterone, dihydrotestosterone, 5-alpha-androstane-3-alpha,17-beta-diol and 5-androstene-3-beta,17-beta-diol, respectively.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    323
    Sequence:
    50:
    MDSKQQTVRL | SDGHFIPILG | FGTYAPQEVP | KSKATEATKI | AIDAGFRHID | 
    100:
    SASMYQNEKE | VGLAIRSKIA | DGTVKREDIF | YTSKVWCTFH | RPELVRVCLE | 
    150:
    QSLKQLQLDY | VDLYLIHFPM | AMKPGENYLP | KDENGKLIYD | AVDICDTWEA | 
    200:
    MEKCKDAGLA | KSIGVSNFNR | RQLEKILKKP | GLKYKPVCNQ | VECHPYLNQG | 
    250:
    KLLDFCRSKD | IVLVAYSALG | SHREKQWVDQ | SSPVLLDNPV | LGSMAKKYNR | 
    300:
    TPALIALRYQ | LQRGVVVLAK | SFSEKRIKEN | MQVFEFQLTS | EDMKVLDDLN | 
    323:
    KNIRYISGSS | FKDHPDFPFW | DEY
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    String:
    Pfam:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Estradiol 17 beta-dehydrogenase 5
    Cat.:
    E0603m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Mouse Estradiol 17 beta-dehydrogenase 5
    Cat.:
    U0603m
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Mouse Estradiol 17 beta-dehydrogenase 5
    Cat.:
    P0603Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Estradiol 17 beta-dehydrogenase 5
    Protein for Mouse Estradiol 17 beta-dehydrogenase 5

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Molecular cloning and characterization of mouse estradiol 17 beta-dehydrogenase (A-specific), a member of the aldoketoreductase family."
      Deyashiki Y. , Ohshima K. , Nakanishi M. , Sato K. , Matsuura K. , Hara A.
      J. Biol. Chem.270:10461-10467(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF N-TERMINUS;PARTIAL PROTEIN SEQUENCE
      strain: BALB/c.
      tissue: Liver.
    2. 2.
      "Structure and activity of the murine type 5 17beta-hydroxysteroid dehydrogenase gene."
      Rheault P. , Charbonneau A. , Luu-The V.
      Biochim. Biophys. Acta1447:17-24(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];FUNCTION;TISSUE SPECIFICITY
      strain: BALB/c.
      tissue: Leukocyte.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Liver.
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