Estradiol 17 beta-dehydrogenase 5 (Protein name
), DHB5_MOUSE from NCBI database.
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Gene name:
Akr1c6(Hsd17b5);
Protein name:
Estradiol 17 beta-dehydrogenase 5;
Alternative:
17-beta-HSD 5;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Monomer.
Function:
Active toward androgens, estrogens, and xenobiotic substrates. Also exhibits low 20 alpha-HSD activity. Shows a-stereospecificity in hydrogen transfer between cofactors and substrates (A-specific). Preferentially catalyzes the reduction of 4-androstenedione, 5-alpha-androstane-3,17-dione, androsterone and dehydroepiandrosterone to testosterone, dihydrotestosterone, 5-alpha-androstane-3-alpha,17-beta-diol and 5-androstene-3-beta,17-beta-diol, respectively.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF N-TERMINUS;PARTIAL PROTEIN SEQUENCE
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];FUNCTION;TISSUE SPECIFICITY